I had the good fortune to be appointed as the 2013 August T. Larsson Guest Researcher at the Swedish University of Agricultural Sciences. Jana, Abhishek, and I are looking forward to this fabulous opportunity to work with Drs. Jerry Ståhlberg, Henrik Hansson, and Mats Sandgren this summer. We anticipate a very productive and insightful few months are ahead!
Announcements regarding research, publication, and successes of the Payne research group members
We have several upcoming presentations on our group's research. Drop by if you are in the area! May 1, 2014 - 10:10 am Grand Ballroom F-G, Hilton Clearwater Beach, FL "Carbohydrate Recognition Mechanisms of Glycoside Hydrolase Modular Domains" 36th Symposium on Biotechnology for Fuels and Chemicals
May 12, 2014 - 9:45 am BPC234 Auditorium, University of Kentucky "Characterizing Glycoside Hydrolase Mechanisms Through Molecular Modeling" Bluegrass Biophysics Symposium
May 12, 2014 - 12:00 pm BBSRB Atrium, University of Kentucky "The Role of Carbohydrate-Aromatic Interactions in Serratia marcescens Chitinases" Bluegrass Biophysics Symposium
May 12, 2014 - 12:00 pm BBSRB Atrium, University of Kentucky "Ligand Binding Dynamics and Directionality in Cellulomonas fimi Family 4 Carbohydrate Binding Modules" Bluegrass Biophysics Symposium
My illustrious (and rather meandering) career is the focus of my alumna profile in the most recent issue of DEXIS Magazine! Some of the highlights include mention of our recent PNAS publication on dynamic glycosylated linker binding to cellulose as well as our collaborative work on chitinases with investigators at the Norwegian University of Life Sciences. Download the PDF, pg 30.
Just quick announcement of upcoming research presentations... If you are around, feel free to drop in! November 1, 2014 - 4pm Room N-320, Agriculture Science Center, University of Kentucky "Molecular mechanisms of protein-protein abiotic stress protection and plant cell wall deconstruction", University of Kentucky, Horticulture Seminar Series
November 4, 2014 - 1:15pm Union Square 14, Hilton, San Francisco, CA "Absolute ligand binding free energy of glycoside hydrolases as a metric for processivity and polysaccharide morphology dependence", AIChE Annual Meeting
November 19, 2014 - 11am Room TBD, University of Kentucky, Paducah Campus "Mechanisms of recalcitrant polysaccharide deconstruction by glycoside hydrolases"
I have been invited to speak at the 4th Annual Enzymatic Hydrolysis of Insoluble Carbohydrates workshop in Dragerup, Denmark. The workshop is organized by faculty and students at the University of Copenhagen and Roskilde University. I will be presenting a talk entitled "Characterizing glycoside hydrolase mechanisms through molecular modeling". My fellow invited speakers are among the most noted researchers our field, and it is truly an honor to be included amongst them. I look forward what promises to be an exciting meeting!
In our recent publication in Proceedings of the National Academy of Sciences, we discuss a computational and experimental examination of glycosylated linker function in multi-modular cellulases. We outline the exciting discovery that cellulase linkers may serve to enhance binding of the enzyme to the cellulose surface through dynamic binding. This finding may prove useful in developing protein engineering strategies for enhanced biomass conversion. This publication, our second in PNAS this year, was featured on the University of Kentucky College of Engineering webpage.
My research is currently featured on the UK College of Engineering webpage. The photo was taken in front of the new UK cluster, DLX. http://www.engr.uky.edu/news/2013/01/faculty-spotlight-interview-with-christina-payne/
Student assignments have been finalized, and thus, it is with great pleasure that I announce the newest member of our research group, Mr. Abhishek Kognole. His biographical information will be available on this website shortly.
This is the first of hopefully many updates on the happenings in the Payne research group at the University of Kentucky. We should be welcoming a new graduate student in the very near future, but at the moment, the group consists of Mr. Suvamay Jana and myself, Dr. Christina M. Payne. I am happy to announce that Mr. Jana has been accepted into the TCBG Computational Biophysics Workshop at UIUC, which he will attend later this month.