Announcements regarding research, publication, and successes of the Payne research group members

Upcoming Presentations

We have several upcoming presentations on our group's research. Drop by if you are in the area! May 1, 2014 - 10:10 am Grand Ballroom F-G, Hilton Clearwater Beach, FL "Carbohydrate Recognition Mechanisms of Glycoside Hydrolase Modular Domains" 36th Symposium on Biotechnology for Fuels and Chemicals

May 12, 2014 - 9:45 am BPC234 Auditorium, University of Kentucky "Characterizing Glycoside Hydrolase Mechanisms Through Molecular Modeling" Bluegrass Biophysics Symposium

May 12, 2014 - 12:00 pm BBSRB Atrium, University of Kentucky "The Role of Carbohydrate-Aromatic Interactions in Serratia marcescens Chitinases" Bluegrass Biophysics Symposium

May 12, 2014 - 12:00 pm BBSRB Atrium, University of Kentucky "Ligand Binding Dynamics and Directionality in Cellulomonas fimi Family 4 Carbohydrate Binding Modules" Bluegrass Biophysics Symposium

Featured in DEIXIS Magazine

My illustrious (and rather meandering) career is the focus of my alumna profile in the most recent issue of DEXIS Magazine! Some of the highlights include mention of our recent PNAS publication on dynamic glycosylated linker binding to cellulose as well as our collaborative work on chitinases with investigators at the Norwegian University of Life Sciences. Download the PDF, pg 30.

Upcoming Presentions

Just quick announcement of upcoming research presentations... If you are around, feel free to drop in! November 1, 2014 - 4pm Room N-320, Agriculture Science Center, University of Kentucky "Molecular mechanisms of protein-protein abiotic stress protection and plant cell wall deconstruction", University of Kentucky, Horticulture Seminar Series

November 4, 2014 - 1:15pm Union Square 14, Hilton, San Francisco, CA "Absolute ligand binding free energy of glycoside hydrolases as a metric for processivity and polysaccharide morphology dependence", AIChE Annual Meeting

November 19, 2014 - 11am Room TBD, University of Kentucky, Paducah Campus "Mechanisms of recalcitrant polysaccharide deconstruction by glycoside hydrolases"

Invited Presentation in Denmark

I have been invited to speak at the 4th Annual Enzymatic Hydrolysis of Insoluble Carbohydrates workshop in Dragerup, Denmark. The workshop is organized by faculty and students at the University of Copenhagen and Roskilde University. I will be presenting a talk entitled "Characterizing glycoside hydrolase mechanisms through molecular modeling". My fellow invited speakers are among the most noted researchers our field, and it is truly an honor to be included amongst them. I look forward what promises to be an exciting meeting!

Glycosylated cellulase linkers dynamically bind cellulose

In our recent publication in Proceedings of the National Academy of Sciences, we discuss a computational and experimental examination of glycosylated linker function in multi-modular cellulases. We outline the exciting discovery that cellulase linkers may serve to enhance binding of the enzyme to the cellulose surface through dynamic binding. This finding may prove useful in developing protein engineering strategies for enhanced biomass conversion. This publication, our second in PNAS this year, was featured on the University of Kentucky College of Engineering webpage.

New graduate student

Student assignments have been finalized, and thus, it is with great pleasure that I announce the newest member of our research group, Mr. Abhishek Kognole.  His biographical information will be available on this website shortly.

A new website for a new group!

This is the first of hopefully many updates on the happenings in the Payne research group at the University of Kentucky. We should be welcoming a new graduate student in the very near future, but at the moment, the group consists of Mr. Suvamay Jana and myself, Dr. Christina M. Payne.  I am happy to announce that Mr. Jana has been accepted into the TCBG Computational Biophysics Workshop at UIUC, which he will attend later this month.