News

Announcements regarding research, publication, and successes of the Payne research group members

Group Meetings

Group meetings with the Kekenes-Huskey group have been scheduled for the semester. We will meet at 175 F. Paul Anderson Tower from 4 to 5 pm on the following days. February 17th - Inacrist Geronimo March 3rd - Abhishek Kognole April 7th - Amir Kucharski May 5th - Yue Yu and Landon Mills

New faces

In the last two months, several new members have joined the group! Graduate students Yue Yu and Landon Mills (co-advised by Derek Englert) are starting new projects looking into the mechanism of a desulfinase. Inacrist Geronimo, who recently received her Ph.D. in Chemistry from Lodz University of Technology, will use molecular simulation to investigate variant stability and specificity in a cytochrome P450. Exciting times!

Congratulations to Tyler on winning the John Walker Biology and Engineering award

Tyler Karnes was selected the inaugural recipient of the 2014 John Walker Biology and Engineering award! Tyler will use the $1000 award to travel to the 2015 AIChE Southern Regional Conference in Clearwater, FL. Here, he will present his research on molecular-level contributions to substrate specificity in enzymatic desulfurization. Congratulations, Tyler!

NSF Award

Prof. Payne was recently awarded her first NSF grant! Our group looks forward to this exciting opportunity to investigate carbohydrate recognition mechanisms of Type B Carbohydrate Binding Modules.

ORAU Ralph E. Powe Award

The Ralph E. Powe award recipients were recently announced, and I was fortunate enough to be named as one. I am very grateful to the ORAU organization for this award and the reviewers who thoughtfully reviewed my application. I look forward to this opportunity to further develop my research group.

Upcoming Presentations

We have several upcoming presentations on our group's research. Drop by if you are in the area! May 1, 2014 - 10:10 am Grand Ballroom F-G, Hilton Clearwater Beach, FL "Carbohydrate Recognition Mechanisms of Glycoside Hydrolase Modular Domains" 36th Symposium on Biotechnology for Fuels and Chemicals

May 12, 2014 - 9:45 am BPC234 Auditorium, University of Kentucky "Characterizing Glycoside Hydrolase Mechanisms Through Molecular Modeling" Bluegrass Biophysics Symposium

May 12, 2014 - 12:00 pm BBSRB Atrium, University of Kentucky "The Role of Carbohydrate-Aromatic Interactions in Serratia marcescens Chitinases" Bluegrass Biophysics Symposium

May 12, 2014 - 12:00 pm BBSRB Atrium, University of Kentucky "Ligand Binding Dynamics and Directionality in Cellulomonas fimi Family 4 Carbohydrate Binding Modules" Bluegrass Biophysics Symposium

Featured in DEIXIS Magazine

My illustrious (and rather meandering) career is the focus of my alumna profile in the most recent issue of DEXIS Magazine! Some of the highlights include mention of our recent PNAS publication on dynamic glycosylated linker binding to cellulose as well as our collaborative work on chitinases with investigators at the Norwegian University of Life Sciences. Download the PDF, pg 30.

Upcoming Presentions

Just quick announcement of upcoming research presentations... If you are around, feel free to drop in! November 1, 2014 - 4pm Room N-320, Agriculture Science Center, University of Kentucky "Molecular mechanisms of protein-protein abiotic stress protection and plant cell wall deconstruction", University of Kentucky, Horticulture Seminar Series

November 4, 2014 - 1:15pm Union Square 14, Hilton, San Francisco, CA "Absolute ligand binding free energy of glycoside hydrolases as a metric for processivity and polysaccharide morphology dependence", AIChE Annual Meeting

November 19, 2014 - 11am Room TBD, University of Kentucky, Paducah Campus "Mechanisms of recalcitrant polysaccharide deconstruction by glycoside hydrolases"

Invited Presentation in Denmark

I have been invited to speak at the 4th Annual Enzymatic Hydrolysis of Insoluble Carbohydrates workshop in Dragerup, Denmark. The workshop is organized by faculty and students at the University of Copenhagen and Roskilde University. I will be presenting a talk entitled "Characterizing glycoside hydrolase mechanisms through molecular modeling". My fellow invited speakers are among the most noted researchers our field, and it is truly an honor to be included amongst them. I look forward what promises to be an exciting meeting!