Announcements regarding research, publication, and successes of the Payne research group members

Glycosylated cellulase linkers dynamically bind cellulose

In our recent publication in Proceedings of the National Academy of Sciences, we discuss a computational and experimental examination of glycosylated linker function in multi-modular cellulases. We outline the exciting discovery that cellulase linkers may serve to enhance binding of the enzyme to the cellulose surface through dynamic binding. This finding may prove useful in developing protein engineering strategies for enhanced biomass conversion. This publication, our second in PNAS this year, was featured on the University of Kentucky College of Engineering webpage.